What are the differences between live attenuated vaccines and inactivated vaccines?
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What are the differences between live attenuated vaccines and inactivated vaccines?
Updated:03/02/2024
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3 Answers
StarVoyager
Updated:22/03/2024

Overview of Vaccine Types

Live Attenuated Vaccines: Live attenuated vaccines consist of a version of the living microbe that has been weakened in the lab so it can’t cause disease. Because these vaccines are so similar to the natural infection that they help prevent, they create a strong and long-lasting immune response. Just one or two doses of most live vaccines can give lifelong protection against a germ and the disease it causes.

However, live vaccines also have some limitations. For example, because they contain a small amount of the weakened virus, they are not recommended for people with weakened immune systems.

Inactivated Vaccines: Inactivated vaccines, on the other hand, use the killed version of the germ that causes a disease. These vaccines are more stable and safer than live vaccines, especially for people with compromised immune systems. However, they usually don’t provide immunity that’s as strong as live vaccines. This means you may need several doses over time (booster shots) to get ongoing immunity against diseases.

Upvote:470
FireSeeker
Updated:19/06/2024

Oh hey, so from what I know, live attenuated vaccines are like giving your body a tiny, harmless taste of the real disease. It’s like your immune system goes to a training camp to learn how to fight the real thing without actually being at risk. These are usually super effective and sometimes you just need one shot! But if someone’s immune system is kinda weak, maybe because of certain meds or illnesses, they might wanna avoid these types cause it could be risky for them. Inactivated ones, though? They’re like a dead virus drill. Totally safe cause nothing’s alive in there, but you might need to get more shots over time to keep up the defense!

Upvote:397
DesertNomad
Updated:05/05/2024

Well, as far as I know, live attenuated vaccines use a weakened form of the virus so it’s alive but not virulent enough to cause disease. This is really effective as it closely mimics a real infection and teaches the immune system how to fight it. But yeah, they can be a bit tricky for people with weaker immune systems. In contrast, inactivated vaccines have killed viruses. They’re safer for those with compromised immune systems, but might require more doses to maintain immunity. Each type has its uses depending on intended safety and efficacy.

Upvote:355