Psoriasis is a chronic skin condition that can significantly impact the quality of life. Systemic therapies are often necessary for severe cases, but they come with potential side effects.

Q: What are systemic therapies for psoriasis?

A: Systemic therapies include medications that affect the entire body. Common types include biologics, immunosuppressants, and traditional systemic agents like methotrexate.

Q: What are the common side effects of systemic therapies?

• 1. Biologics: Infections, injection site reactions, allergic reactions.
• 2. Methotrexate: Nausea, liver toxicity, blood disorders.
• 3. Cyclosporine: Kidney damage, high blood pressure, increased risk of infections.

Q: How do these side effects impact patients?

A: Side effects can lead to discontinuation of treatment, increased healthcare costs, and reduced compliance. Patients may also experience anxiety or depression due to these side effects.

Q: Are there any long-term effects of systemic therapies?

A: Some patients may experience long-term effects, especially with prolonged use of traditional systemic agents which can lead to chronic conditions such as liver disease or renal impairment.

Q: How can side effects be managed?

A: Regular monitoring by healthcare providers, dose adjustments, and supportive therapies can help manage side effects.

Potential Side Effects Summary:

Statistical Data:

• 30% of patients on methotrexate report gastrointestinal issues.
• 10%-15% of patients on biologics experience serious infections.

Mind Map of Side Effects:

Systemic Therapies for Psoriasis ➔ Types of Therapies ➔ Side Effects ➔ Management Strategies ➔ Long-term Effects