1 Answers
SunsetRider
Updated:23/04/2024
Amyloidosis is a rare but serious condition characterized by the buildup of amyloid proteins in organs and tissues.
Treatments for Amyloidosis
- Medications:
- Chemotherapy drugs such as melphalan
- Targeted therapies like daratumumab for AL amyloidosis
- Immunosuppressive therapy
- Steroids to reduce inflammation
- Supportive treatments:
- Diuretics for heart issues
- Antidepressants for mood stabilization
- Palliative care for end-stage symptoms
- Stem cell transplantation:
- High-dose chemotherapy followed by stem cell transplant can be considered for eligible patients.
- Organ Transplant:
- In severe cases affecting organs, a transplant may be necessary (e.g., heart, kidney).
When to Seek Treatment
It’s important to seek treatment if you experience any of the following symptoms:
- Unexplained fatigue or weakness
- Shortness of breath or heart palpitations
- Swelling in the legs or abdomen
- Numbness or tingling in the hands or feet
- Unintentional weight loss
Table of Treatment Options
| Treatment Type | Description | Indications |
|---|---|---|
| Chemotherapy | Uses drugs to kill amyloid-producing cells | AL amyloidosis |
| Stem Cell Transplant | Replaces damaged cells with healthy stem cells | For eligible patients with AL amyloidosis |
| Organ Transplant | Replacement of severely damaged organs | End stage organ dysfunction |
| Supportive Care | Management of symptoms and improving quality of life | All stages of amyloidosis |
Statistics on Amyloidosis
- Annual incidence rate: Approximately 10-20 cases per million people
- Prevalence of AL amyloidosis: About 4-12% of patients with multiple myeloma
- 5-year survival rate without treatment: < 20%
- 5-year survival rate with treatment: > 50%
Mind Map: Steps in Seeking Treatment
- Recognize Symptoms
- Fatigue
- Heart issues
- Nerve Problems
- Consult a Physician
- General practitioner
- Specialist referral (hematologist, cardiologist)
- Get Diagnosed
- Blood tests
- Biopsy (fat or bone marrow)
- Imaging studies
- Discuss Treatment Options
- Medications
- Transplantation
- Supportive care
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